- Info
Publications
-
Peer-reviewed journal papers
- Mills E., Truong K. Analysis and regulation of
amoeboid-like cell motility using synthetic
Ca2+-sensitive proteins. Cell
Calcium. in press
- Nagaraj S., Mills E., Wong S.S and Truong K.
Programming membrane fusion and subsequent apoptosis into
mammalian cells. ACS Synthetic Biology. in
press
- Wong SS., Mills E., Truong K. Simultaneous assembly of two
target proteins using split inteins. Protein
Engineering, Design and Selection. 26(3):207-13. (2013)
- Mills E, Pham E., Nagaraj S. and Truong K. Engineered
networks of synthetic and natural proteins to control cell
migration. ACS Synthetic Biology. 6(1):211–220.
(2012)
- Pham E. and Truong K. Engineered regulation of lysozyme by
the SH3-CB1 binding interaction. Protein Engineering,
Design and Selection. 25(6):307-11. (2012). Read article [.pdf, 196
kb].
- Nagaraj S., Wong S.S. and Truong K. Parts-based assembly of
synthetic transmembrane proteins in mammalian cells. ACS
Synthetic Biology. 4(1):111-117. (2012).
- Pham E., Wong S.S., Nagaraj S. and Truong K. Effects
of rapamycin-induced oligomerization of Parvalbumin, Stim1 and Orai1 in
puncta formation. Cell Calcium. 51:418-425.
(2012). Read article [.pdf, 1952
kb].
- Mills E., Chen X., Pham E., Wong S.S, and Truong K.
Engineering a photoactivated caspase-7 for rapid induction of
apoptosis. ACS Synthetic Biology. 3(1):75-82.
(2012).
- Wong S.S., Kotera I., Mills E., Suzuki H. and Truong
K. Split-intein mediated re-assembly of genetically
encoded Ca2+ indicators. Cell
Calcium. 51:57-64. (2012). Read article [.pdf, 1006
kb].
- Shahravan S.H., Li I.T., Truong K. and Shin J.A.
FRep: a fluorescent protein-based bioprobe for in
vivo detection of protein-DNA interactions.
Analytical Chemistry. 83:9643-50. (2011). Read article [.pdf, 2384
kb].
- Mills E. and Truong K. Ca2+-mediated synthetic
biosystems offer protein design versatility, signal specificity and
pathway rewiring. Chemistry and Biology. 18:
1611-1619. (2011). Read article [.pdf, 1026
kb].
- Pham E., Mills E. and Truong K. A synthetic
photoactivated protein to generate local or global
Ca2+ signals. Chemistry and
Biology. 18:880-90. (2011). Read article [.pdf, 1365
kb]. Previewed by Romanin C.
- Wong S.S. and Truong K. Fluorescent protein-based
methods for on-plate screening of gene
insertion. PLoS ONE. 5(12):e14274.
(2010). Read article
[.pdf, 1119 kb]
- Chen X., Pham E. and Truong K. TEV
protease-facilitated stoichiometric delivery of multiple genes using a
single expression vector. Protein Science.
19:2379-88. (2010). Read article [.pdf,
2988 kb]
- Mills E., Pham E. and Truong K. Structure based design
of a Ca2+-sensitive RhoA protein that controls cell
morphology. Cell Calcium.
48:195–201. (2010). Read article [.pdf, 880
kb]
- Li I.T., Mills E and Truong K. A computational tool
for Monte Carlo simulations of biomolecular reaction networks modeled
on physical principles. IEEE Transactions in
Nanobioscience 9(1), 24-30. (2010). Read article [.pdf, 562 kb].
Supplemental materials [.pdf, 48
kb].
- Mills E and Truong K. Engineering
Ca2+/calmodulin-mediated modulation of protein translocation
by overlapping binding and signaling peptide
sequences. Cell Calcium.
47:369–377. (2010). Read article [.pdf, 1370
kb]
- Mills E. and Truong K. Cascading signaling pathways improve
the fidelity of a stochastically and deterministically simulated
molecular RS latch. BMC Syst Biol. 3(1):72. (2009).
Read article [.pdf, 432
kb]
- Mills E. and Truong K. Rate and extent of protein
localization is controlled by peptide-binding domain association
kinetics and morphology. Protein Sci. 18(6):1252-60.
(2009). Read article [.pdf, 398
kb]
- Li I.T., Pham E., Chiang J.J. and Truong K. FRET evidence
that an isoform of caspase-7 binds but does not cleave its
substrate. Biochem Biophys Res Commun. 373(4):325-9.
(2008). Read article
[.pdf, 665 kb]
- Li I.T., Shum W. and Truong K. 160-fold acceleration of the
Smith-Waterman algorithm using a field programmable gate array
(FPGA). BMC Bioinformatics. 8(1):185. (2007). Read article [.pdf, 286
kb]
- Pham E., Chiang J.J., Li I.T., Shum W. and Truong K. A
computational tool for designing FRET protein biosensors by rigid-body
sampling of their conformational space. Structure.
15(5), 515-23. (2007). Read article [.pdf, 752
kb]
- Li I.T., Ranjith K.R. and Truong K. Sequence reversed
peptide from CaMKK binds to calmodulin in reversible
Ca2+-dependent manner. Biochem Biophys Res
Commun. 352(4):932-5. (2007). Read article [.pdf,
437 kb]
- Chiang J.J., Li I.T. and Truong K. Creation of circularly
permutated yellow fluorescent proteins using fluorescence screening and
a tandem fusion template. Biotechnology Letters
28(7), 471-5. (2006). Read article [.pdf, 256
kb]
- Chiang J.J. and Truong K. Computational modeling of a new
fluorescent biosensor for caspase proteolytic activity improves dynamic
range. IEEE Transactions in Nanobioscience 5(1),
41-5. (2006). Read article
[.pdf, 597 kb]
- Chiang J.J. and Truong K. Using co-cultures expressing
fluorescence resonance energy transfer based protein biosensors to
simultaneously image caspase-3 and
Ca2+ signaling. Biotechnology Letters
27(16), 1219 - 1227. (2005). Read article [.pdf, 452
kb]
- Truong K., Khorchid A. and Ikura M. Fluorescent
cassette-based strategy for engineering of multiple domain fusion
proteins. BMC Biotechnology 3(1): 8. (2003). Read article [.pdf, 682 kb]
- Truong K. and Ikura M. Domain fusion analysis by applying
relational algebra to protein sequence and domain databases.
BMC Bioinformatics 4(1): 16. (2003). Read article [.pdf, 446
kb]
- Stavropoulos D.J., Bradshaw P.S., Li X. Pasic I., Truong K., Ikura
M., Ungrin M. and Meyn M. The Bloom syndrome helicase BLM
interacts with TRF2 in ALT cells and promotes telomeric DNA
synthesis. Human Molecular Genetics 11, 3135-44.
(2002). Read article [.pdf, 1495 kb]
- Truong K. and Ikura M. The cadherin superfamily
database. Journal of Structural and Functional
Genomics 2, 135-43. (2002). Read article [.pdf, 309 kb]
- Truong K. and Ikura M. Identification and characterization
of subfamily-specific signatures in a large protein superfamily by a
hidden Markov model approach. BMC Bioinformatics
3(1): 1. (2002). Read article [.pdf, 846
kb]
- Truong K., Sawano A., Mizuno H., Hama H., Tong K.I., Mal T.K.,
Miyawaki A. and Ikura M. FRET-based in vivo Ca2+
imaging by a new calmodulin-GFP fusion molecule. Nature
Structural Biology 8,1069-73. (2001). Read article [.pdf, 2029
kb]
- Yap K.L., Kim J., Truong K., Sherman M., Yuan T and Ikura M.
Calmodulin target database. Journal of Structural
and Functional Genomics 1,8-14. (2000). Read article [.pdf, 796 kb]
Peer-reviewed conference papers
- Truong K, Pham E. Exploring the conformational space of
FRET biosensors for improved designs. Proceedings of SPIE
Photonics West Conference. (2008).
- Li, I.T., Chiang J.J., and Truong K. FRET evidence that an
isoform of caspase-7 binds but does not cleave its substrate.
28th Annual International IEEE Engineering Conference in Medicine
and Biology. (2006). Read article[.pdf, 720
kb]
- Chiang J.J., Li, I.T., Pham E. and Truong K. The FPMOD: a
modeling tool for sampling the conformational space of fusion
proteins. 28th Annual International IEEE Engineering
Conference in Medicine and Biology. (2006). Read article [.pdf, 394
kb]
- Chiang J.J., Studniberg M., Shaw J., Seto S. and Truong K.
Hardware accelerator for genomic sequence alignment.
28th Annual International IEEE Engineering Conference in Medicine
and Biology. (2006). Read article [.pdf, 303 kb]
Reviews
- Pham E., Li I.T. and Truong K. Computational modeling
approaches for studying of synthetic biological networks.
Current Bioinformatics. May. 3 (2): 130-141. (2008). Read review [.pdf, 335
kb]
- Li I.T., Pham E. and Truong K. Protein biosensors based on
the principle of fluorescence resonance energy transfer for monitoring
cellular dynamics. Biotechnology Letters. Dec. 28
(24):1971-82. (2006). Read review [.pdf, 284
kb]
- Truong K. and Ikura M. The use of FRET imaging microscopy
to detect protein-protein interactions and protein conformational
changes in vivo. Current Opinions in Structural
Biology 11,573-8. (2001). Read review [.pdf, 504 kb]
- Tepass U., Truong K., Godt D., Ikura M. and Peifer M.
Cadherins in embryonic and neural morphogenesis.
Nature Reviews Molecular Cell Biology 1,91-100. (2000). Read review [.pdf, 1614
kb]
Book Chapters
- Pham E. and Truong K. Design of fluorescent fusion protein
probes. Methods Mol Biol. 591:69-91 (2010). Read book chapter [.pdf,
866kb]
- Li I.T., Pham E. and Truong K. Current approaches for
engineering proteins with diverse biological properties.
Adv Exp Med Biol. 620 : 18-33 . (2007). Read book chapter [.pdf, 294 kb]
- Truong K., Sawano A., Miyawaki A. and Ikura M.
Ca2+ indicators based on calmodulin-fluorescent
protein fusions. Methods in Molecular Biology. Protein
Engineering Protocols. 71-82. (2007). Read book chapter
[.pdf, 1320 kb]
- Hoeflich K.P., Truong K., Ikura M. Ca2+ as a
second messenger. new reporters for Ca2+ (cameleons and
camgaroos). Cell Biology: A Laboratory Handbook.
(2003). Book chapter (proofs unavailable)
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